Peanut-allergic preschool children who received peanut oral immunotherapy as part of a clinical trial were 19 times more likely to successfully add peanut-containing foods into their diets, researchers said.
Peanut oral immunotherapy in a capsule is moving closer to regulatory approval in the United States. The therapy brings hope – not for a cure – but of lives made less vulnerable.
In a long-term follow-up study, oral immunotherapy (OIT) patients who were treated for up to five food allergies were able to maintain a high level of desensitization to their allergens, even those taking very low “doses” of their allergens.
Patients taking the drug had one-third the number of reactions of a placebo group while doing OIT
All of the participants in the Phase II trial were able to tolerate nearly 2 peanut kernels at the end of two months.
Testing OIT in such a young population has never been done before, but results show that it’s worth it.
Study author Mimi Tang says these results could lead to effective treatment for peanut allergies.
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